Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophies in an animal model, NCN SONATA grant (2024-2027), Proncipal Investigator - Xiaonan Liu PhD
Development and implementation of an algorithm for predicting the effectiveness of the epithelialization process after corneal surgical procedures based on the condition of limbal stem cells and corneal limbal vessels in an in vivo confocal microscopy study and optical coherence tomography of vessels, Doktorat Wdrożeniowy (2024-2028), PhD student Dominik Dygas, Supervisor Adrian Smedowski MD PhD
Biology of neuronal connexins – regulation of cellular transport by proteasome and endosome blockers in the excitotoxicity-induced neurodegeneration of retinal ganglion cells, SUM research grant (2022-2025), Principal Investigator - Adrian Smedowski MD PhD
Oral L-tyrosine supplementation to support the retinal function in axial myopia, Doktorat Wdrożeniowy (2022-2026), PhD student Bartosz Machna Msc, Supervisor Adrian Smedowski MD PhD
The role of Brain Derived Neurotrophic Factor (BDNF) and electrical synapses in the neuroprotective activity of Escitalopram in a mouse model of retinal ischemia, NCN Preludium BIS (2022-2026), Principal Investigator - Adrian Smedowski MD PhD
Interaction between selective estrogen receptor modulators (SERMs) and FasR/FasL pathway in the retina of ovariectomized rats under ischemic conditions, NCN Preludium (2022-2025), Principal Investigator - Piotr Rodak MD, Supervisor - Adrian Smedowski MD PhD
Finalized Projects
CRISPR/Cas9 for inhibiting transthyretin (TTR) expression in the eye with TTR-amyloidosis, Umeå University Sweden collaborative grant (2022-2024)
Screening for new therapeutic targets in inherited retinal diseases based on protein-protein interactions analysis, NCN POLS (2021-2023)
Development of an innovative experimental gene therapy for glaucoma treatment – the role of RNA-binding proteins, NCN SONATA (2018-2021)
Potential mechanism of chronic adnexa inflammation induced by preservative-free prostaglandin analogue eyedrops, SANTEN (2018-2019)
Schwann cells mediated neuroprotection of retinal ganglion cells in the animal model of glaucoma, SUM (2012-2015)
Tolerability of preservative-free prostaglandin analogue eyedrops, SANTEN (2013-2015)